• Ann Fr Anesth Reanim · Dec 2007

    Case Reports

    [Treatment of a septic shock due to multiresistant Acinetobacter baumannii with tigecycline in combination].

    • T Leclerc, J-P Perez, B Debien, P Clapson, and B Lenoir.
    • Service d'anesthésie-réanimation, HIA Percy, 101, avenue H. Barbusse, 92141 Clamart cedex, France. thomas.leclerc@m4x.org
    • Ann Fr Anesth Reanim. 2007 Dec 1; 26 (12): 1056-8.

    AbstractWe report a case of pulmonary and bloodstream infection due to multiresistant Acinetobacter baumannii six days after a severe trauma. Clinical condition transiently improved following antimicrobial treatment with ticarcillin-clavulanate and rifampicin. However, a septic shock developed on the fourth day due to the emergence of a strain only sensible to cotrimoxazole, colistin and tigecycline. Cure was achieved after a two week treatment with piperacillin-tazobactam, cotrimoxazole and tigecycline. This case shows that combined antimicrobial therapy including tigecycline can be relevant in some severe pulmonary infections due to multiresistant A. baumannii.

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