• Intensive care medicine · Mar 2023

    Review

    How to manage coagulopathies in critically ill patients.

    • Julie Helms, Toshiaki Iba, Jean Marie Connors, Satoshi Gando, Marcel Levi, Ferhat Meziani, and Jerrold H Levy.
    • Université de Strasbourg (UNISTRA), Faculté de Médecine, Hôpitaux Universitaires de Strasbourg, Service de Médecine Intensive-Réanimation, Nouvel Hôpital Civil, 1, place de l'Hôpital, 67091, Strasbourg Cedex, France. Julie.helms@chru-strasbourg.fr.
    • Intensive Care Med. 2023 Mar 1; 49 (3): 273290273-290.

    AbstractCoagulopathy is a severe and frequent complication in critically ill patients, for which the pathogenesis and presentation may be variable depending on the underlying disease. Based on the dominant clinical phenotype, the current review differentiates between hemorrhagic coagulopathies, characterized by a hypocoagulable and hyperfibrinolysis state, and thrombotic coagulopathies with a systemic prothrombotic and antifibrinolytic phenotype. We discuss the differences in pathogenesis and treatment of the common coagulopathies.© 2023. Springer-Verlag GmbH Germany, part of Springer Nature.

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