• Curr Opin Anaesthesiol · Oct 2023

    Review

    Endometriosis - a painful disease.

    • Lydia Coxon, Emma Evans, and Katy Vincent.
    • Nuffield Department of Women's & Reproductive Health, University of Oxford, Oxford, UK.
    • Curr Opin Anaesthesiol. 2023 Oct 1; 36 (5): 595601595-601.

    Purpose Of ReviewThis review looks to overview advances in endometriosis-associated pain, both in understanding the pain mechanisms involved and increasing treatment options with well designed clinical trials and meta-analyses.Recent FindingsOur understanding of endometriosis-associated pain has progressed from a purely nociceptive model to an awareness that both neuropathic and nociplastic mechanisms can be present for some people with endometriosis. Clinical trials and meta-analyses have demonstrated efficacy of surgical treatments and hormonal therapies. It is notable that currently, the basic science and clinical trials are not cross-fertilising.SummaryFollowing growth in other areas of chronic pain, there have been significant advances in our understanding of endometriosis-associated pain. However, there remains lots to explore and we are currently a long way from our goal of timely personalized holistic multidisciplinary treatment for all sufferers of endometriosis-associated pain.Copyright © 2023 The Author(s). Published by Wolters Kluwer Health, Inc.

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