• Clin Med (Lond) · Sep 2023

    Review

    SARS-CoV-2 vaccines and myocarditis.

    • Agata Katarzyna Sularz, Alina Hua, and Tevfik Ismail.
    • Guy's and St Thomas' NHS Foundation Trust, St Thomas' Hospital, London UK.
    • Clin Med (Lond). 2023 Sep 1; 23 (5): 495502495-502.

    AbstractThe development of safe and effective vaccines against severe acute respiratory syndrome-coronavirus 2 (SARS-CoV-2) was a major turning point in the fight against the Coronavirus 2019 (COVID-19) pandemic. However, pharmacovigilance has revealed a small but significant incidence of cardiac inflammation manifesting clinically as myocarditis or pericarditis, particularly in younger vaccine recipients. The incidence is the highest among men under age 40 within a week of receiving the second dose of the mRNA vaccine. In this review, we summarise the evidence for, and guidelines in relation to, SARS-CoV2 vaccine-related myocarditis.© Royal College of Physicians 2023. All rights reserved.

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