• Curr Pain Headache Rep · Mar 2024

    Review

    The Prevalence and Clinical Phenotypes of Cluster Headache in Relation with Latitude.

    • Yi-Chia Liaw, Shih-Pin Chen, and Shuu-Jiun Wang.
    • Department of Neurology, Neurological Institute, Taipei Veterans General Hospital, Taipei, Taiwan.
    • Curr Pain Headache Rep. 2024 Mar 5.

    Purpose Of ReviewPrevious studies have indicated a possible link between the prevalence of cluster headache (CH) and sunlight exposure. However, this theory has yet to be tested systemically. In this article, we aim to examine how latitude affects the prevalence and phenotypes of CH.Recent FindingsTo our knowledge, there is by far no article describing the effect of latitude on disease phenotype; thus, we performed a literature review. We noted positive effects of latitude on 1-year prevalence, the proportion of chronic CH, and the proportion of miosis and/or ptosis. Latitude may affect the phenotypic presentations of cluster headache, probably partially mediated via temperature and sunlight variations. Still, other factors, such as environmental exposure to smoking and the genetic difference between the Eastern and Western populations, may participate in the pathogenesis and clinical manifestations of CH.© 2024. The Author(s).

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