• Obstet. Gynecol. Clin. North Am. · Jun 2014

    Review

    The perils of opioid prescribing during pregnancy.

    • Marjorie Meyer.
    • Fletcher Allen Health Care and the University of Vermont, 111 Colchester Avenue, Burlington, VT 05401, USA. Electronic address: Marjorie.meyer@uvm.edu.
    • Obstet. Gynecol. Clin. North Am. 2014 Jun 1;41(2):297-306.

    AbstractChronic opioid therapy during pregnancy is perilous, but not simply because of neonatal effects: it is perilous because women are at particular risk for misprescription, misuse, dependence, overdose, and death. Opioids may be teratogens and should be avoided in the periconception period. Accidental childhood poisoning and purposeful teen experimentation are increased with opioid prescriptions in the home. Risks to pregnancy span the pre- and periconception period; neonatal risk following in utero opioid exposure is well documented. When the authors' patients request opioids for chronic pain, they care for them in a comprehensive and compassionate matter, which often will require therapeutic approaches other than chronic opioid therapy.Copyright © 2014 Elsevier Inc. All rights reserved.

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