• Ann. N. Y. Acad. Sci. · Dec 2001

    Review Multicenter Study

    Early lung cancer action project: annual screening using single-slice helical CT.

    • C I Henschke, D F Yankelevitz, D M Libby, D McCauley, M Pasmantier, N K Altorki, J P Smith, and O S Miettinen.
    • Department of Radiology, Weill Medical College of Cornell University, New York, New York 10021, USA.
    • Ann. N. Y. Acad. Sci. 2001 Dec 1;952:124-34.

    AbstractThe advent of helical CT imaging held promise for the early diagnosis, and thereby, for enhanced curability of lung cancer--a highly fatal disease. In 1993, the Early Lung Cancer Action Project (ELCAP) was initiated and experimentally screened a cohort of 1,000 high-risk persons. Here we summarize the results of the baseline and annual repeat CT screening of these 1,000 subjects. CT-based screening (compared to traditional radiology) was clearly shown to enhance the detection of lung cancer at earlier and more curable stages. A discussion follows of the meaning of the results and possible future screening protocols.

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