• Ann Indian Acad Neur · Apr 2013

    Sedation in neurological intensive care unit.

    • Birinder S Paul and Gunchan Paul.
    • Department of Neurology, Dayanand Medical College, Ludhiana, India.
    • Ann Indian Acad Neur. 2013 Apr 1; 16 (2): 194-202.

    AbstractAnalgesia and sedation has been widely used in intensive care units where iatrogenic discomfort often complicates patient management. In neurological patients maximal comfort without diminishing patient responsiveness is desirable. In these patients successful management of sedation and analgesia incorporates a patient based approach that includes detection and management of predisposing and causative factors, including delirium, monitoring using sedation scales, proper medication selection, emphasis on analgesia based drugs and incorporation of protocols or algorithms. So, to optimize care clinician should be familiar with the pharmacokinetic and pharmacodynamic variables that can affect the safety and efficacy of analgesics and sedatives.

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