• CMAJ · Jul 2019

    Change in moderate alcohol consumption and quality of life: evidence from 2 population-based cohorts.

    • Xiaoxin I Yao, Michael Y Ni, Felix Cheung, Joseph T Wu, C Mary Schooling, Gabriel M Leung, and Herbert Pang.
    • School of Public Health, Li Ka Shing Faculty of Medicine (Yao, Ni, Cheung, Wu, Schooling, Leung, Pang), and The State Key Laboratory of Brain and Cognitive Sciences (Ni), The University of Hong Kong, Hong Kong Special Administrative Region, China; Graduate School of Public Health and Health Policy (Schooling), City University of New York, New York, NY.
    • CMAJ. 2019 Jul 8; 191 (27): E753-E760.

    BackgroundAlthough the association of moderate alcohol consumption with specific disorders, such as cardiovascular disease and cancers, has been well documented, the evidence of the broader impact of alcohol consumption on health-related quality of life is less clear. Our objective was to examine the association of drinking patterns with changes in physical and mental well-being across populations.MethodsWe conducted a multilevel analysis with multivariate responses in the population-representative FAMILY Cohort in the Hong Kong Special Administrative Region, China, to examine the association between alcohol drinking patterns across 2 waves (2009-2013) (i.e., quitters, initiators, persistent drinkers, persistent former drinkers and lifetime abstainers) and changes in physical and mental well-being (Physical and Mental Component Summary of the 12-Item Short Form Health Survey [SF-12]). Analyses were stratified by sex. We validated findings using a nationally representative cohort in the United States, the National Epidemiologic Survey on Alcohol and Related Conditions (NESARC, 2001-2005).ResultsIn the FAMILY Cohort (n = 10 386; median follow-up 2.3 yr), the change in mental well-being was more favourable in female quitters than in lifetime abstainers (β = 1.44, 95% confidence interval [CI] 0.43 to 2.45; mean score change of +2.0 for quitters and +0.02 for lifetime abstainers). This association was validated in the NESARC (n = 31 079; median follow-up 3.1 yr) (β = 0.83, 95% CI 0.08 to 1.58; mean score change of -1.1 for quitters and -1.6 for lifetime abstainers).InterpretationThe change in mental well-being was more favourable in female quitters, approaching the level of mental well-being of lifetime abstainers within 4 years of quitting in both Chinese and American populations.© 2019 Joule Inc. or its licensors.

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