• Epileptic Disord · Dec 2003

    Stereotactic surgical approach to hypothalamic hamartomas.

    • Ruben I Kuzniecky and Barton L Guthrie.
    • UAB Epilepsy Center, Department of Neurology, University of Alabama at Birmingham, Birmingham, Alabama, USA.
    • Epileptic Disord. 2003 Dec 1; 5 (4): 275-80.

    AbstractHypothalamic hamartomas are often associated to a progressive epileptic encephalopathy. Non-invasive data indicates that destruction or isolation of the hamartoma may stop seizures. We present data on patients who underwent stereotactic radiofrequency with or without endoscopy. Epilepsy improved in 60% of patients with minimal morbidity. This approach was less successful in large lesions. These results indicate that this approach should be considered in patients with small/medium lesions.

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