• Souza Neto E P EP Service d'anesthésie-réanimation, hôpital cardiovasculaire et pneumologique Louis-Pradel, BP Lyon Monchat, 69394 cedex 03, Lyon, France. edmundo@rockefe, J Neidecker, and J J Lehot.
• Service d'anesthésie-réanimation, hôpital cardiovasculaire et pneumologique Louis-Pradel, BP Lyon Monchat, 69394 cedex 03, Lyon, France. edmundo@rockefeller.univ-lyon1.fr <edmundo@rockefeller.univ-lyon1.fr>
• Ann Fr Anesth Reanim. 2003 May 1; 22 (5): 425-52.

ObjectivesTo review current data on the heart rate and blood pressure variability.Data SourcesSearch through Medline databases of articles in french or english.Data SelectionOriginal articles and case reports were selected according to their quality and main advances. The articles were analysed in order to obtain current data about the methods of study and clinical application of blood pressure and heart rate variability.Data SynthesisVarious regulatory systems in the cardiovascular system play crucial roles in controlling and assuring adequate perfusion of the peripheral tissues. Among them the baroreceptor reflex is the most important regulatory mechanism in the short-term control of the heart rate and blood pressure, and operates through the autonomic nervous system. The gain of the cardiac baroreflex further referred to, as baroreflex sensitivity is an interesting way to study this system. Unfortunately, with our current knowledge, it is not possible to predict the instantaneous output of the baroreceptor in response to instantaneous changes in input within a frequency range of physiological importance. The fast Fourier transform can describe variables as the sum of elementary oscillatory components and it has been established as practical clinical methods for detecting abnormalities in cardiovascular control. A time-frequency distribution provides an indication of how the spectral energy distribution varies with time and it is an interesting tool in non-stationary data. One of the major motivations behind spectral analysis is the hope that the combination of time-domain and frequency-domain analyses will provide dynamical informations about the relation between blood pressure and heart rate.

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