• Eur Spine J · Mar 2020

    Inflammatory mediators and the risk of falls among older women with acute low back pain: data from Back Complaints in the Elders (BACE)-Brazil.

    • Zille de Queiroz Bárbara B 0000-0003-1014-1512 Department of Physical Therapy, Post-Graduate Program in Rehabilitation Sciences, School of Physical Ed, de Britto Rosa Nayza Maciel NM Department of Physical Therapy, Post-Graduate Program in Rehabilitation Sciences, School of Physical Education, Physical Therapy and Occupa, Daniele Sirineu Pereira, Renata Antunes Lopes, Leopoldino Amanda Aparecida Oliveira AAO Department of Physical Therapy, Post-Graduate Program in Rehabilitation Sciences, School of Physical Education, Physical Therapy , Ronaldo Luiz Thomasini, Diogo Carvalho Felício, Lygia Paccini Lustosa, and Pereira Leani Souza Máximo LSM Department of Physical Therapy, Post-Graduate Program in Rehabilitation Sciences, School of Physical Education, Physical Therapy and Occupa.
    • Department of Physical Therapy, Post-Graduate Program in Rehabilitation Sciences, School of Physical Education, Physical Therapy and Occupational Therapy, Universidade Federal de Minas Gerais (UFMG), Av. Antônio Carlos, 6627, Belo Horizonte, MG, CEP 31270-901, Brazil. leanismp.bh@terra.com.br.
    • Eur Spine J. 2020 Mar 1; 29 (3): 549-555.

    PurposeTo investigate the association between plasma levels of inflammatory cytokines (interleukin [IL]-1-β, IL-6, tumor necrosis factor [TNF]-α, and the soluble TNF receptor 1 [sTNF-R1]), disability, and risk of falls in older women with acute low back pain (LBP).MethodsThis cross-sectional study comprised a subsample of older women from the Back Complaints in the Elders international cohort study. Plasma levels of IL-1-β, IL-6, TNF-α, and sTNF-R1 were measured using enzyme-linked immunosorbent assays. Pain was assessed using the Numerical Pain Scale and McGill Pain Questionnaire, while disability was measured using the Roland Morris Questionnaire and gait speed. Risk of falls was estimated using the Physiological Profile Assessment. Linear regression model was used to verify the association between independent variables and fall risk.ResultsOne hundred and ten women (aged 69.97 ± 5.5 years) with acute LBP were included. The regression model showed an association between the risk of falls and IL-6 levels, pain, gait speed, and years of education. It also explained 21.2% of risk of falls variance. The model equation was: fall risk = 1.28 + (0.19 IL-6) + (0.02 quality of pain) + (- 0.71 gait speed) + (-0 .17 educational level).ConclusionsThis study showed an association between risk of falls and IL-6, pain, gait speed, and educational level in older women with LBP. These slides can be retrieved under Electronic Supplementary Material.

      Pubmed     Full text   Copy Citation     Plaintext  

      Add institutional full text...

    Notes

     
    Knowledge, pearl, summary or comment to share?
    300 characters remaining
    help        
    You can also include formatting, links, images and footnotes in your notes
    • Simple formatting can be added to notes, such as *italics*, _underline_ or **bold**.
    • Superscript can be denoted by <sup>text</sup> and subscript <sub>text</sub>.
    • Numbered or bulleted lists can be created using either numbered lines 1. 2. 3., hyphens - or asterisks *.
    • Links can be included with: [my link to pubmed](http://pubmed.com)
    • Images can be included with: ![alt text](https://bestmedicaljournal.com/study_graph.jpg "Image Title Text")
    • For footnotes use [^1](This is a footnote.) inline.
    • Or use an inline reference [^1] to refer to a longer footnote elseweher in the document [^1]: This is a long footnote..

    hide…

Want more great medical articles?

Keep up to date with a free trial of metajournal, personalized for your practice.
1,624,503 articles already indexed!

We guarantee your privacy. Your email address will not be shared.