Lancet neurology
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Randomized Controlled Trial Multicenter Study
Pallidal neurostimulation in patients with medication-refractory cervical dystonia: a randomised, sham-controlled trial.
Cervical dystonia is managed mainly by repeated botulinum toxin injections. We aimed to establish whether pallidal neurostimulation could improve symptoms in patients not adequately responding to chemodenervation or oral drug treatment. ⋯ Medtronic.
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Randomized Controlled Trial Multicenter Study
Safety and efficacy of LY2951742, a monoclonal antibody to calcitonin gene-related peptide, for the prevention of migraine: a phase 2, randomised, double-blind, placebo-controlled study.
Migraine remains poorly treated, with few effective preventive drugs available. We assessed the safety and efficacy of LY2951742, a fully humanised monoclonal antibody to calcitonin gene-related peptide, for migraine prevention. ⋯ Arteaus Therapeutics.