International journal of surgery
-
Excessive bleeding is an important cause of morbidity and mortality after cardiac surgery. Bleeding after cardiac surgery is multifactorial. Adherence to the proverbial 6 Ps remains the cornerstone of any strategy for management of postoperative bleeding after cardiac surgery. ⋯ Plasma levels of NOAC >30 ng/ml necessitate specific therapeutic interventions to tackle excessive bleeding attributed to NOAC intake. Current recommendation is to consider using specific reversal agent if available. Otherwise, use of prothrombin complex concentrates is recommended.
-
Editorial Review
The role of normothermic machine perfusion in liver transplantation.
To expand the donor pool of suitable organs for transplantation, there is an increased interest in utilizing extended criteria donor grafts (ECD). Ex-situ machine perfusion has shown to be a promising new modality in the organ preservation field to reduce injury and recover ECD liver grafts. Machine perfusion (MP) is considered a significant improvement in the field of transplantation over the past 20 years. ⋯ Machine perfusion moved from the experimental phase to a more mature phase after safety was confirmed by initial clinical trials. Now, it is time to confirm its superiority and cost-effectiveness before a broader clinical use. In this paper we review the history, current status including outcomes of all clinical trials, limitations, and future trends of normothermic machine preservation.
-
Editorial
Management of urology during COVID-19 pandemic: A perspective from Sichuan Province, China.
Since first reported in Dec.2019 in Wu Han, China, Novel Coronavirus has captured most cities in China. On Feb.1.2020, National Health Commission of the People's Republic of China (NHCC) officially termed the novel coronavirus as COVID-19, which is in accordance with World Health Organization (WHO). Until 14:35, Feb, 21, the number of diagnosed cases was 76,178 and 2247 died, among which 75,568 and 2239 were reported in China respectively with an estimated mortality of 2.9%. A comprehensive introduction of management strategy involving patients and their family, ward, protection and psychological adjustment of medical staff in urology department of West China Hospital during COVID-19 epidemic was summarized in this article, through which we hope could provide reference for other medical centers.