Contemporary clinical trials
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Contemp Clin Trials · Feb 2021
Meta AnalysisRemdesivir for the treatment of COVID-19: A systematic review and meta-analysis of randomized controlled trials.
The nucleotide analogue prodrug remdesivir was among the first antiviral therapies to be tested in randomized controlled trials (RCTs) for COVID-19. We performed a meta-analysis to understand efficacy and safety. ⋯ Patients given remdesivir are more likely to demonstrate recovery and were associated with higher rates of hospital discharge, but not with significant reduction in mean time to clinical improvement or mortality.