International journal of obesity : journal of the International Association for the Study of Obesity
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Randomized Controlled Trial Multicenter Study
Efficacy and safety of topiramate in combination with metformin in the treatment of obese subjects with type 2 diabetes: a randomized, double-blind, placebo-controlled study.
To investigate the efficacy and safety of topiramate in obese subjects with type 2 diabetes treated with metformin. ⋯ Topiramate was effective for weight reduction and improvement in glycemic control in obese subjects with type 2 diabetes treated with metformin monotherapy. Further study in obese diabetics is warranted.