Cardiovascular therapeutics
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Randomized Controlled Trial Pragmatic Clinical Trial
The Effect of a Cardiovascular Polypill Strategy on Pill Burden.
Recent trials of cardiovascular polypills in high-risk populations show improvements in the use of cardiovascular preventive treatments, compared to usual care. We describe patterns of pill burden in Australian practice, define the impact of polypill therapy on pill burden, and explore how physicians add medication to polypill therapy. ⋯ A cardiovascular polypill in contemporary Australian practice reduces cardiovascular and total pill burdens, despite frequent prescription of additional medications.