Journal of gastrointestinal cancer
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J Gastrointest Cancer · Mar 2021
Impact of the COVID-19 Pandemic on Elective Surgery for Colorectal Cancer.
To investigate the impact of the COVID-19 pandemic on patients with colorectal cancer undergoing elective surgery. ⋯ During the COVID-19 pandemic, the number of patients undergoing elective surgery for colorectal cancer was reduced. However, the tumor stage of patients did not change substantially. We suggest that the clinical diagnosis and treatment of colorectal cancer should strictly comply with national and professional standards.
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J Gastrointest Cancer · Jan 2021
Incidence, Survival and Prognostic Factors of Oesophagogastric Cancer.
Oesophagogastric cancer is one of the leading causes of cancer death worldwide due to its aggressive nature. Despite the high mortality rate, there is limited information regarding this cancer in Brunei. ⋯ Prognosis of oesophagogastric cancer remains poor. Addressing late detection and improve endoscopic surveillance and awareness of symptoms may help improve prognosis and mortality.
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J Gastrointest Cancer · Sep 2020
ReviewRecommendations on Management of Locally Advanced Rectal Cancer During the COVID-19 Pandemic: an Iranian Consensus.
Today, the rapid outbreak of COVID-19 is the leading health issue. Patients with cancer are at high risk for the development of morbidities of COVID-19. Hence, oncology centers need to provide organ-based recommendations for optimal management of cancer in the COVID-19 era. ⋯ Our recommendation may provide a guide for oncology centers of developing countries for better management of locally advanced rectal cancer.
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J Gastrointest Cancer · Jun 2020
Utility of Prognostic Prediction Models in the Terminal Stage of Gastrointestinal Cancer.
For patients receiving palliative care, information about prognosis is important to help them set priorities and expectations for care and to assist clinicians in decision-making. The purpose of this study was to investigate prognostic models applicable to the terminal stage of gastrointestinal cancer, especially in terms of accuracy of prediction regarding 3-week survival. ⋯ PPI and BPS were found to be accurate prediction models for short-term survival of terminal gastrointestinal cancer patients.
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J Gastrointest Cancer · Jun 2020
Review Multicenter StudyImmune Checkpoint Inhibitors in Locally Advanced, Unresectable, and Metastatic Upper Gastrointestinal Malignancies.
Upper gastrointestinal (UGI) malignancies including esophageal, gastroesophageal junction (GEJ), and gastric cancers have a poor prognosis in the metastatic setting. Treatment with cytotoxic chemotherapy remains the treatment of choice in the first-line setting with the addition of trastuzumab, a monoclonal antibody against HER-2, if the tumor is HER2-positive. Before the era of checkpoint inhibitors, there were only few treatment options after failure of the first-line systemic therapy. ⋯ Based on recent and ongoing studies, eligible patients who have progressed beyond the first-line cytotoxic chemotherapy may benefit from immunotherapy. This review outlines the checkpoint inhibitors that are currently or previously being investigated for patients with metastatic UGI cancers.