Nature reviews. Urology
-
Nature reviews. Urology · Jul 2014
Prostate cancer: intriguing data on inflammation and prostate cancer.
A new case–control study shows that inflammation on biopsy is associated with diagnosis of prostate cancer. We think a large population-based prospective study, specifically designed to investigate the longitudinal association between inflammation and subsequent onset of prostate cancer, is required to elucidate the true relationship between inflammation and prostate carcinogenesis.
-
Nature reviews. Urology · Jun 2014
Prostate cancer: surgery versus observation for localized prostate cancer.
A key study comparing radical prostatectomy and watchful waiting for prostate cancer has been updated with extended follow-up observation, demonstrating substantial benefits of surgery for reduced mortality mainly in younger men, but also reduced requirement for palliative treatment in older men. These findings should be interpreted within the current scenario of prostate cancer diagnosis and treatment.