Chest
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Recent medical society opinions have questioned the use of early antimicrobials in patients with sepsis, but without septic shock. ⋯ Delays in first antimicrobial administration in patients with suspected infection are associated with rapid increases in likelihood of progression to septic shock. Additionally, qSOFA score has higher specificity than SIRS score for predicting septic shock, but is associated with a worse outcome, even when patients receive early antibiotics.