Anesthesia and analgesia
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Anesthesia and analgesia · Nov 2012
Volumetric three-dimensional ultrasound imaging of the anatomy relevant for thoracic paravertebral block.
While ultrasound imaging of the thoracic paravertebral space in 2-dimensional (D) mode allows examination of the paravertebral anatomy in the transverse or sagittal axis, volumetric 3D ultrasound imaging provides multiplanar images in several orthogonal (perpendicular) planes and may provide additional anatomical information. In this imaging study we assessed the feasibility of 3D ultrasound imaging of the anatomical area relevant to the thoracic paravertebral block. ⋯ Volumetric 3D ultrasound imaging of the thoracic paravertebral space is feasible and provides more detailed spatial anatomical information than 2D ultrasound imaging.
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Anesthesia and analgesia · Nov 2012
Ginkgo biloba extract attenuates hyperalgesia in a rat model of vincristine-induced peripheral neuropathy.
Chemotherapy-induced peripheral neuropathy is a common, dose-limiting side effect of cancer chemotherapeutic drugs. Hyperalgesia is a common component of neuropathic pain. Ginkgo biloba extract (GBE) is an oriental herbal medicine that has various pharmacological actions. In this study, we evaluated the effects of oral GBE on hyperalgesia in a rat model of vincristine-induced neuropathy. ⋯ This study demonstrates that oral administration of GBE is associated with a dose-dependent antihyperalgesic effect on mechanical and cold stimuli in a rat model of vincristine-induced neuropathy.