Wiener klinische Wochenschrift
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Wien. Klin. Wochenschr. · Feb 2025
Conservative treatment of knee arthrofibrosis according to a cellular cytokine-based model : A retrospective pilot evaluation.
Arthrofibrosis (AF) is a relatively frequent complication after knee surgery, leading to painful limitation of joint mobility. Currently, intense stretching is performed in many patients, without improvements in mobility. A novel concept, established on a cellular, cytokine-based model, advocates to consider the warning function of pain and to terminate forced joint mobilization to disrupt the cycle of arthrofibrosis. Based on these findings, our clinic developed a comprehensive antifibrotic treatment protocol. The aim of this analysis was to evaluate the patients treated so far. ⋯ Based on this pilot evaluation, the comprehensive conservative AF program seems to have high potential. Therefore, larger future studies should be conducted to validate this concept.
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Wien. Klin. Wochenschr. · Feb 2025
A rare case of a rectal neuroendocrine neoplasm growing within a lipoma with ulcerative lesions.
Neuroendocrine neoplasms (NENs) are a heterogeneous group of tumors with different immunophenotypes, morphological features, clinical presentations, and outcomes. Therefore, the diversity of NENs can easily confuse clinicians and lead to misdiagnosis. ⋯ Through the review of this case and relevant literature, we further analyze the growth pattern of NENs and lipomas. Additionally, we hope to enhance clinicians' awareness of a NEN that grew insidiously within a lipoma with surface ulcerative lesions, to make accurate diagnoses and treatments in time.
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Wien. Klin. Wochenschr. · Feb 2025
Observational StudyMaternal and neonatal outcomes in kidney transplant recipients: a single-center observational study.
Pregnancy poses a high risk for adverse maternal and neonatal outcomes in kidney transplant recipients (KTRs), and data on long-term allograft functions compared to the healthy population are still limited. Therefore, we aimed to conduct a comparative analysis of maternal and neonatal outcomes in KTRs. ⋯ The KTRs exhibit comparable neonatal mortality and NICU admission rates but have higher rates of preeclampsia and preterm birth. Importantly, graft functions worsen significantly during postpartum follow-up.
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General practice/family medicine has recently been recognized as a medical discipline in Austria. This paper is a short report on the prevailing understanding of its goals and subjects, comparing the Austrian perception with international definitions. It comments on shortcomings and introduces an outline for the development of a revised professional theory. ⋯ Now it is the fragmentation that extensive specialization entails that gives a new meaning to generalist, contextual and patient-centered medicine. This change needs to be analyzed and understood. A description of the responsibilities, tasks and very specific methods unique to the discipline will be developed, which should enable the sensible, contemporary use of general practice/family medicine for the benefit of patients and the healthcare system.