Lancet
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Meta Analysis
Antivirals for treatment of severe influenza: a systematic review and network meta-analysis of randomised controlled trials.
The optimal antiviral drug for treatment of severe influenza remains unclear. To support updated WHO influenza clinical guidelines, this systematic review and network meta-analysis evaluated antivirals for treatment of patients with severe influenza. ⋯ World Health Organization.
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Meta Analysis
Antivirals for post-exposure prophylaxis of influenza: a systematic review and network meta-analysis.
Antiviral post-exposure prophylaxis with neuraminidase inhibitors can reduce the incidence of influenza and the risk of symptomatic influenza, but the efficacy of the other classes of antiviral remains unclear. To support an update of WHO influenza guidelines, this systematic review and network meta-analysis evaluated antiviral drugs for post-exposure prophylaxis of influenza. ⋯ World Health Organization.
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Formerly incarcerated people have exceptionally poor health profiles and are at increased risk of preventable mortality when compared with their general population peers. However, not enough is known about the epidemiology of mortality in this population-specifically the rates, causes, and timing of death in specific subgroups and regions-to inform the development of targeted, evidence-based responses. We aimed to document the incidence, timing, causes, and risk factors for mortality after release from incarceration. ⋯ Australia's National Health and Medical Research Council.
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Pharmacotherapy provides an option for adults with overweight and obesity to reduce their bodyweight if lifestyle modifications fail. We summarised the latest evidence for the benefits and harms of weight-lowering drugs. ⋯ 1.3.5 Project for Disciplines of Excellence, West China Hospital, Sichuan University.
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Infants and young children born prematurely are at high risk of severe acute lower respiratory infection (ALRI) caused by respiratory syncytial virus (RSV). In this study, we aimed to assess the global disease burden of and risk factors for RSV-associated ALRI in infants and young children born before 37 weeks of gestation. ⋯ EU Innovative Medicines Initiative Respiratory Syncytial Virus Consortium in Europe.