The Journal of family practice
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YES, TO SOME DEGREE-BUT IT IS OF UNCERTAIN CLINICAL SIGNIFICANCE. OVER A PERIOD OF 6 MONTHS, METFORMIN MODESTLY REDUCED WEIGHT (-2.1 KG) AND BODY FAT MASS (-1.9%), BUT NOT BODY MASS INDEX (BMI) OR LEAN BODY MASS, IN ADOLESCENTS WHO WERE OVERWEIGHT OR OBESE. THIS IS COMPARABLE TO LIFESTYLE INTERVENTIONS (DIET AND EXERCISE) SUPPORTED WITH > 26 HOURS OF COUNSELING, WHICH MODESTLY IMPROVED BMI BUT NOT WEIGHT. (STRENGTH OF RECOMMENDATION [SOR]: A, BASED ON A LARGE META-ANALYSIS OF RANDOMIZED CONTROLLED TRIALS [RCTS] OF VARIABLE QUALITY).
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The complexity of this disorder poses a clinical challenge like few others.
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This study supports the use of an ICS/LABA as needed for adults with intermittent, mild persistent, and moderate persistent asthma.
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It took a dermatoscopic examination followed by an e-consultation and shave biopsy to arrive at the diagnosis.
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Case Reports
14-year-old girl • history of bullying • lack of social support • multiple linear scars on breasts • Dx?
► History of bullying ► Lack of social support ► Multiple linear scars on breasts.