Journal of neurosurgery
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Journal of neurosurgery · Aug 2002
Multicenter Study Clinical TrialStabilization of disease progression by hydroxyurea in patients with recurrent or unresectable meningioma.
The management of certain meningiomas of the skull base and those involving the dural venous sinuses remains a challenge. In recent reports it has been suggested that hydroxyurea chemotherapy can cause regression of unresectable and recurrent meningiomas. The authors report their experience in using hydroxyurea for the treatment of patients with recurrent or unresectable meningiomas. ⋯ Although tumor regression appears uncommon, these results indicate that hydroxyurea may arrest progression of unresectable or recurrent benign meningiomas.