Journal of neurosurgery
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Journal of neurosurgery · Jan 2005
Case ReportsLong-term results of gamma knife surgery for growth hormone-producing pituitary adenoma: is the disease difficult to cure?
The authors conducted a study to determine the long-term results of gamma knife surgery for residual or recurrent growth hormine (GH)-producing pituitary adenomas and to compare the results with those after treatment of other pituitary adenomas. ⋯ Gamma knife surgery was effective and safe for the control of tumors; however, normalization of GH and IGF-1 secretion was difficult to achieve in cases with large tumors and low-dose radiation. Gamma knife radiosurgery is thus indicated for small tumors after surgery or medication therapy when a relatively high-dose radiation is required.
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Journal of neurosurgery · Jan 2005
Prolonged survival in a subgroup of patients with brain metastases treated by gamma knife surgery.
The authors analyzed the factors involved in determining prolonged survival (> or = 24 months) in patients with brain metastases treated by gamma knife surgery (GKS). ⋯ Aggressive local therapy with GKS, repeated GKS, and GKS plus surgery can achieve increased survival in a subgroup of patients with stable primary disease, no third-organ involvement, and long primary-brain secondary intervals.
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Journal of neurosurgery · Jan 2005
A simple method for predicting imaging-based complications following gamma knife surgery for cerebral arteriovenous malformations.
The authors studied the relationship between dose planning parameters and complications in the treatment of cerebral arteriovenous malformations (AVMs). ⋯ The integral dose could be used as a guideline for the prescription dose. Arguments are made for maximizing the prescription dose for the long-term safety of the patient.
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Journal of neurosurgery · Jan 2005
Long-term complications after gamma knife surgery for arteriovenous malformations.
The authors analyzed of the long-term complications that occur 2 or more years after gamma knife surgery (GKS) for intracranial arteriovenous malformations (AVMs). ⋯ Incomplete obliteration of the nidus is the most important factor associated with delayed hemorrhagic complications. Partial obliteration does not seem to reduce the risk of hemorrhage. Complete obliteration can be complicated by delayed cyst formation, especially if high maximal treatment doses have been administered.
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Journal of neurosurgery · Jan 2005
Analysis of long-term outcomes and prognostic factors in patients with non-small cell lung cancer brain metastases treated by gamma knife radiosurgery.
The authors conducted a study to evaluate the long-term outcomes and prognostic factors for survival in a large series of patients treated by gamma knife surgery (GKS) for non-small cell lung cancer (NSCLC) brain metastases. ⋯ Gamma knife surgery is a useful treatment for brain metastases from NSCLC.