Spine
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Randomized Controlled Trial Multicenter Study Comparative Study
The treatment of disc herniation-induced sciatica with infliximab: results of a randomized, controlled, 3-month follow-up study.
A randomized controlled trial. ⋯ The results of this randomized trial do not support the use of infliximab for lumbar radicular pain in patients with disc herniation-induced sciatica.
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Comparative Study
Biomechanical assessment of the pediatric cervical spine under bending and tensile loading.
Cadaveric head-neck complexes from pediatric donors aged 2-12 years were subjected to a test battery consisting of nondestructive flexion-extension bending, nondestructive tensile step-and-hold tests, and tensile distraction loading to failure. ⋯ The current study provides valuable new information on the response and tolerance of the pediatric cervical spine to quasi-static flexion-extension and tensile distraction loading.
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Randomized Controlled Trial Comparative Study
Predictors and modifiers of treatment effect influencing sick leave in subacute low back pain patients.
Modifying effects in multivariate analyses of a randomized controlled trial. ⋯ The spine clinic intervention seems to have a main effect on work absenteeism via interacting with the concerns of being unable to work.
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Comparative Study Clinical Trial
Temporary external transpedicular fixation of the lumbosacral spine: a prospective, longitudinal study in 330 patients.
In this study, 330 patients with incapacitating low back pain underwent temporary external transpedicular fixation (TETF) of the lumbosacral spine in a prospective trial. ⋯ In this heterogeneous group of chronic patients with low back pain, TETF of the spine (including a placebo trial) does not appear to be of value in selecting suitable candidates for spinal fusion.
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Comparative Study
Long-term results of disc excision for recurrent lumbar disc herniation with or without posterolateral fusion.
A retrospective study assessing the long-term outcomes of repeat surgery for recurrent lumbar disc herniation. ⋯ Repeat surgery for recurrent sciatica is effective in cases of true recurrent disc herniation. Disc excision alone is recommended for managing recurrent disc herniation.