Spine
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Comparative Study
Biomechanical analysis of posterior fixation techniques in a 360 degrees arthrodesis model.
A biomechanical study to assess the ability of posterior fixation techniques to stabilize a functional spine unit (FSU) after insertion of an anterior load-sharing device. ⋯ Using a load-sharing interbody implant, translaminar facet screws are equivalent to bilateral pedicle screws in resisting motion in all three planes. Translaminar facet screws and bilateral pedicle screws offer greater stabilization in all three planes compared with unilateral pedicle screws and a single plate.
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Comparative Study
Biomechanical changes at adjacent segments following anterior lumbar interbody fusion using tapered cages.
A biomechanical evaluation of anterior cages in a calf lumbar spine model. ⋯ Statistically significant changes in intradiscal pressures and motion were found at the adjacent levels following a single-level stand-alone ALIF procedure using paired LT cages.
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Randomized Controlled Trial Multicenter Study Comparative Study
Comparison of OP-1 Putty (rhBMP-7) to iliac crest autograft for posterolateral lumbar arthrodesis: a minimum 2-year follow-up pilot study.
A prospective, randomized, controlled, multicenter clinical study. ⋯ This study represents the first clinical trial to demonstrate the safety and similarity of OP-1 Putty as a replacement for autogenous bone graft in the posterolateral fusion environment with a minimum of 2-year follow-up. OP-1 Putty was able to achieve osteoinduction leading to a radiographically solid fusion in the absence of autogenous iliac crest bone graft in 55% of the patients at 24 and 36 months. These results compare favorably to the historical fusion rates reported for uninstrumented arthrodesis in this challenging clinical scenario.
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Randomized Controlled Trial Multicenter Study Comparative Study
The treatment of disc herniation-induced sciatica with infliximab: results of a randomized, controlled, 3-month follow-up study.
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Randomized Controlled Trial Comparative Study
Predictors and modifiers of treatment effect influencing sick leave in subacute low back pain patients.
Modifying effects in multivariate analyses of a randomized controlled trial. ⋯ The spine clinic intervention seems to have a main effect on work absenteeism via interacting with the concerns of being unable to work.