Spine
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A retrospective review. ⋯ Harvesting cancellous autograft anteriorly from the lumbar spine using a trephine technique appears to be safe and reliable, with satisfactory fusion rates. Iliac crest graft harvesting with its attendant morbidity is avoided.
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Animal study. ⋯ PMMA caused relatively little necrotic exothermal effect. The presence of PMMA with barium sulfate induces a mild foreign body reaction. The use of a balloon tamp creates a void by displacing pieces of bone, which may result in a lower incidence of intravascular cement leak.
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Experimental animal study. OBJECTIVE.: Evaluate osteopromotive properties of a beta-tricalcium phosphate (TCP) implant with different osteogenic substances in an animal study. ⋯ The combination of beta-TCP and bone marrow has superior osteopromotive properties to venous blood or concentrated mononuclear cells and can be used effectively as a substitute to iliac crest graft.
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Cyclic mechanical stress (CMS) was applied to cultured nucleus pulposus and anulus fibrosus cells, and the production of inflammatory agents by these cells was evaluated. ⋯ The results of this study suggested that CMS might be involved in the pathomechanism of pain induction of lumbar disc diseases.