Spine
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Review Comparative Study
The subaxial cervical spine injury classification system: a novel approach to recognize the importance of morphology, neurology, and integrity of the disco-ligamentous complex.
The classification system was derived through a literature review and expert opinion of experienced spine surgeons. In addition, a multicenter reliability and validity study of the system was conducted on a collection of trauma cases. ⋯ The Sub-axial Injury Classification and Severity Scale provides a comprehensive classification system for subaxial cervical trauma. Early validity and reliability data are encouraging.
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Comparative Study
Variability in rates of arthrodesis for patients with thoracolumbar spine fractures with and without associated neurologic injury.
Retrospective cohort study using a large clinical database. ⋯ Hospital teaching status and spine fracture volume affected rates of spine arthrodesis in thoracolumbar fracture patients with and without neurologic injury. Variability in fusion rate for thoracolumbar spine trauma appears to be lower than that reported for elective spine procedures, especially in the presence of a neurologic injury.
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Comparative Study
Spinal cord morphology and dynamics during cervical laminoplasty: evaluation with intraoperative sonography.
An intraoperative sonographic study for evaluating spinal cord decompression status was conducted. ⋯ Intraoperative sonography during laminoplasty appears to be very useful for evaluating spinal cord decompression status. Our original classification system based on restoration patterns of the space ventral to the spinal cord is considered to be practical for predicting neurologic improvement in cervical compressive myelopathy.
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Randomized Controlled Trial Multicenter Study Comparative Study
Recombinant activated factor VII in spinal surgery: a multicenter, randomized, double-blind, placebo-controlled, dose-escalation trial.
Randomized, placebo-controlled, double-blind, multicenter, Phase IIa study. ⋯ No safety concerns were indicated for the use of rFVIIa in patients at all doses tested; rFVIIa reduced adjusted blood loss and adjusted transfusions during spinal surgery.
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Comparative Study
ProDisc-L total disc replacement: a comparison of 1-level versus 2-level arthroplasty patients with a minimum 2-year follow-up.
This is a retrospective analysis of data that was collected prospectively from 2 concurrent FDA IDE lumbar arthroplasty clinical trials performed at a single center. ⋯ This study was unable to identify a statistically significant difference in outcome between 1- and 2-level ProDisc arthroplasty patients in a cohort from a single center. The equality of clinical effectiveness between 1- and 2-level ProDisc has yet to be determined.