Spine
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Retrospective analysis of 73 standalone lateral lumbar interbody fusion (LLIF) procedures to identify any association between the amount of coronal curve correction and lumbosacral plexus injuries and/or postoperative pain. ⋯ 4.
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Case report and description of technique. ⋯ Microendoscopic techniques can be extended to excise lesions of the spine. It is a safe procedure in experienced hands. The advantages are minimal morbidity, minimal postoperative pain and discomfort, less analgesic dependence, and better cosmesis. The authors recommend this technique for accessible lesions involving the spine.
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Histological and ultrastructural evaluation of cell morphologies at the concave and convex side of apical intervertebral discs (IVD) of adolescent idiopathic scoliosis (AIS). ⋯ This study was able to show significant differences in cell morphologies in the AF on both sides and in correlation to the different tilt angles. The type and magnitude of load seem to influence disc cells. Further studies are required to provide more information on disc and cell changes in scoliosis.
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We used a complete spinal cord transection model and locomotor function, histological, and immunohistochemical examinations to evaluate the effects of local injection of lentivirus/LINGO-1-short hairpin RNA (VL) on rats with spinal cord injury (SCI). ⋯ Local injection of lentivirus/LINGO-1-short hairpin RNA after complete transection of spinal cord resulted in meaningful histological and functional outcomes in rats. The mechanism of VL protection may be related to its promotion of axonal sprouting, remyelination, and cell survival.
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Follow-up of animals after surgically initiated scoliosis. ⋯ This study establishes a rat lumbar scoliosis model via asymmetric load. This method develops lumbar scoliosis in a short time and maintains the essential elements along the curve. It is suitable for the investigation of scoliosis.