Spine
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Cross sectional study. ⋯ Although limited by small sample size, the objective parameter, MRI index, can be a potential imaging biomarker used to identify possible pain generators. This study presents a potential new application of MR imaging in identifying pain generators of patients with chronic low back pain.
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Retrospective cohort study of the American College of Surgeons National Surgical Quality Improvement Program database from 2005 to 2010 that included 1861 patients who had undergone elective posterior lumbar fusion. ⋯ 3.
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A register-based national study. ⋯ 3.
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Animal experimental study. ⋯ The NP voxel count proved to be a valid parameter to assess disc degeneration quantitatively in a needle puncture model. The mean NP T2-RT does not change significantly in needle-puncture-induced degenerated IVDs. IVDs can be segmented into different tissue components according to their innate T2-RT.
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Observational Study
Transient low back pain development during standing predicts future clinical low back pain in previously asymptomatic individuals.
Longitudinal, observational. ⋯ Transient LBP development during prolonged standing is a positive predictive factor for future clinical LBP in previously asymptomatic individuals. Individuals who experience transient LBP during standing may be considered a "preclinical" group who are at increased risk for future LBP disorders.