Intensive care medicine
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Intensive care medicine · Sep 2001
Letter Case ReportsGemcitabine-associated diffuse alveolar hemorrhage.
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Intensive care medicine · Aug 2001
Multicenter Study Comparative StudyTreatment of acute methanol poisoning with fomepizole.
To assess the efficacy and safety of fomepizole, a competitive alcohol dehydrogenase inhibitor, in methanol poisoning and to test the hypothesis that fomepizole obviates the need for hemodialysis in selected patients. ⋯ Fomepizole appears safe and effective in the treatment of methanol-poisoned patients. If our results are confirmed in prospective analyses, hemodialysis may prove unnecessary in patients presenting without visual impairment or severe acidosis.
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Intensive care medicine · Aug 2001
Multicenter Study Clinical TrialTotal extracorporeal arteriovenous carbon dioxide removal in acute respiratory failure: a phase I clinical study.
To evaluate the safety and efficacy of pumpless extracorporeal arteriovenous carbon dioxide removal (AVCO2R) in subjects with acute respiratory failure and hypercapnia. ⋯ Pumpless extracorporeal AVCO2R is capable of providing complete extracorporeal removal of carbon dioxide during acute respiratory failure, while maintaining mild to moderate hypercapnia. Applied in conjunction with mechanical ventilation and permissive hypercapnia, AVCO2R resulted in normalization of arterial PCO2 and pH and permitted significant reductions in the level of mechanical ventilation.