Neurosurgery
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Randomized Controlled Trial Clinical Trial
Mild hypothermia as a protective therapy during intracranial aneurysm surgery: a randomized prospective pilot trial.
To conduct a pilot trial of mild intraoperative hypothermia during cerebral aneurysm surgery. ⋯ Mild hypothermia during cerebral aneurysm surgery is feasible in nonobese patients and is well tolerated. Our results indicate that a multicenter trial enrolling 300 to 900 patients with acute aneurysmal SAH will be required to demonstrate a statistically significant benefit with mild intraoperative hypothermia.