Journal of the American Academy of Dermatology
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J. Am. Acad. Dermatol. · Nov 2004
Randomized Controlled Trial Multicenter Study Clinical TrialPimecrolimus cream 1% in the treatment of intertriginous psoriasis: a double-blind, randomized study.
Inverse psoriasis can be difficult to treat because of the high sensitivity of intertriginous areas to cutaneous side effects, such as irritation and striae. Pimecrolimus, a well-tolerated, nonatrophogenic, skin-selective inflammatory cytokine inhibitor, has been shown to be effective in the treatment of psoriasis when applied topically under occlusion. ⋯ Pimecrolimus cream 1% is an effective treatment for inverse psoriasis with a rapid onset of action, and is safe and well-tolerated.