Preventive medicine
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Preventive medicine · Apr 2014
Multicenter Study Comparative StudyBudget impact and cost-utility analysis of universal infant rotavirus vaccination in Spain.
Rotavirus is not included in the Spanish mass infant vaccination schedule but has also not been economically evaluated for its inclusion. We analysed cost-utility of the universal infant rotavirus vaccination using RotaTeq® versus no vaccination in Spain. We also carried out a budget impact analysis and determined the effect on results of different variables introduced in the model. ⋯ The introduction of the vaccination using RotaTeq® as a universal infant vaccination would increase the annual health care budget in 10.43 million euro and would result in a gain of an additional Quality Adjusted Life Year at a cost of 280,338€ from the healthcare system perspective and 210,167€ from the societal perspective. The model was stable to variable modifications. To sum up, according to our model and estimates, the introduction of a universal infant rotavirus vaccination with RotaTeq® in Spain would cause a large impact on the health care budget and would not be efficient unless significant variations in vaccine price, vaccine efficacy and/or utilities took place.
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Preventive medicine · Mar 2014
Randomized Controlled Trial Multicenter StudyThe impact of product information and trials on demand for smokeless tobacco and cigarettes: evidence from experimental auctions.
Epidemiological and toxicological evidence suggests lower risk of smokeless tobacco (ST) products compared to cigarettes. Less is known, however, about consumer perceptions and use of novel forms of ST, including snus and dissolvable tobacco. ⋯ These findings suggest that credible and effective communications about tobacco harm reduction should reinforce the negative effects of smoking.
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Preventive medicine · Mar 2014
Randomized Controlled Trial Multicenter StudyWeight gain prevention in the school worksite setting: results of a multi-level cluster randomized trial.
To describe the effectiveness, reach and implementation of a weight gain prevention intervention among public school employees. ⋯ This study supports that a multi-level intervention integrated within the organizational culture can be successfully implemented and prevent weight gain in public high school employees.
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Preventive medicine · Feb 2014
Randomized Controlled Trial Multicenter StudyImpact of a web-based intervention supplemented with text messages to improve cancer prevention behaviors among adolescents: results from a randomized controlled trial.
To assess the impact of a web-based intervention supplemented with text messages to reduce cancer risk linked with smoking, unhealthy diet, alcohol consumption, obesity, sedentary lifestyle and sun exposure. ⋯ ISRCTN27988779.
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Preventive medicine · Feb 2014
Multicenter StudyRelationships between changes in time spent walking since middle age and incident functional disability.
To examine the relationship between changes in time spent walking since middle age and incident functional disability. ⋯ An increase in time spent walking among sedentary adults is significantly associated with a lower risk of incident functional disability.