Preventive medicine
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Preventive medicine · Dec 2024
Assessing the association between cigarette smoking and blood C-reactive protein levels using restructured cohort data.
Cigarette smoke exposure is known to induce inflammation, leading to elevated levels of inflammatory markers such as white blood cell (WBC) count and C-reactive protein (CRP). Despite extensive research on this relationship, longitudinal studies are limited. We aimed to explore the association between cigarette smoke exposure and WBC count and CRP levels by restructuring community cohort data. ⋯ In a community cohort, cigarette smoking was associated with elevated WBC count. However, CRP levels did not consistently reflect inflammation associated with cigarette smoking.
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Preventive medicine · Dec 2024
ReviewAn atlas on risk factors for gastrointestinal cancers: A systematic review of Mendelian randomization studies.
Gastrointestinal cancers are one of the most frequent cancer types and seriously threaten human life and health. Recent studies attribute the occurrence of gastrointestinal cancers to both genetic and environmental factors, yet the intrinsic etiology remains unclear. Mendelian randomization is a powerful well-established statistical method that is based on genome-wide association study (GWAS) to evaluate the causal relationship between exposures and outcomes. In the present study, we aimed to conduct a systematic review of Mendelian randomization studies investigating any causal risk factors for gastrointestinal cancers. ⋯ Larger, well-designed Mendelian randomization studies are practical in determining the causal status of risk factors for diseases.
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Preventive medicine · Dec 2024
Association of watching sports games with subsequent health and well-being among adults in Japan: An outcome-wide longitudinal approach.
Although the health benefits of playing sports are well-known, the association between watching sports and health is not well understood. We examined the longitudinal association of watching sports with 20 different health and well-being outcomes. ⋯ Despite the observed detrimental association between watching sports and cardiometabolic health, which should be interpreted cautiously and studied further, the study findings suggest that watching sports could be a new modifiable protective factor for developing healthy lifestyles and improving mental well-being.
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Preventive medicine · Dec 2024
ReviewSystematic review of the evidence on physical activity prescriptions for youth.
Despite the well-documented benefits of physical activity (PA), globally, only 20 % of youth engage in sufficient PA. Reviews support the benefits of PA prescriptions on promoting adults' PA, but no comparable reviews exist on studies among youth. This systematic review 1) assesses the state of the evidence regarding PA prescriptions from healthcare practitioners on youths' PA; and 2) identifies gaps to inform future research and practice. ⋯ There is insufficient research on healthcare practitioner delivered PA prescriptions to promote youths' PA to determine effectiveness. Future research with objectively measured PA and more diverse youth samples would advance the evidence.
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Preventive medicine · Dec 2024
Randomized Controlled TrialOrganized cervical cancer screening: A randomized controlled trial assessing the effect of sending invitation letters.
To evaluate the effect of implementing two modalities of organized Cervical Cancer Screening (CCS) program on screening uptake after a six-month delay. ⋯ The implementation of an organized screening based on an invitation letter resulted in a modest increase in participation among non-adherent women six months later.