The American journal of emergency medicine
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Multicenter Study Clinical Trial
Validation of the Vancouver Chest Pain Rule using troponin as the only biomarker: a prospective cohort study.
The objective of this study is to evaluate the accuracy of the Vancouver Chest Pain Rule using troponin as the only biomarker in an emergency department (ED) setting. ⋯ The Vancouver Chest Pain Rule with troponin as the only biomarker identified a sizable low-risk cohort. However, sensitivity was lower than that identified in the original derivation study and was considered insufficient to enable safe early discharge. Modifications to the tool would be required if troponin was incorporated as the only biomarker.