Resuscitation
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Infusion of bone marrow mesenchymal stem cells (MSCs) improves myocardial function following myocardial infarction (MI). The mechanisms, however, remain controversial. This study was to investigate changes of MSCs in vivo after administration into myocardial infarcted rats. Our hypothesis was that MSCs might differentiate into contractile myocytes and improve myocardial function in vivo. ⋯ MSCs can differentiate into beating cardiomyocytes in a rat model of MI and improve myocardial function.