European journal of anaesthesiology
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The concentration range of dexamethasone that inhibits neuromuscular blockade (NMB) and sugammadex reversal remains unclear. ⋯ Acute bolus administration of dexamethasone at clinical concentrations had no effect on NMB or on sugammadex reversal.
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Meta Analysis Comparative Study
Deep vs. moderate neuromuscular blockade during laparoscopic surgery: A systematic review and meta-analysis.
Previous studies have reported that deep neuromuscular block (posttetanic-count 1 to 2 twitches) improves surgical conditions during laparoscopy compared with moderate block (train-of-four count: 1 to 2 twitches). However, comparisons of surgical conditions were made using different scales and assessment intervals with variable results. ⋯ Deep block was associated with excellent or good surgical rating more frequently than moderate block. However, this finding was not consistent on subgroup analyses based on frequencies of assessment of surgical conditions and abdominal pressure. Further studies are required to address the heterogeneity and power shortage demonstrated by the trial sequential analysis.
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Observational Study
Duration of the action of rocuronium in patients with BMI of less than 25: An observational study.
Duration of rocuronium action directly correlates with BMI.
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