Journal of hepatology
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Journal of hepatology · Nov 1998
Randomized Controlled Trial Clinical TrialEffects of increasing blood hemoglobin levels on systemic hemodynamics of acutely anemic cirrhotic patients.
In experimental portal hypertension, blood hemoglobin levels have been shown to influence the hyperdynamic circulatory state. The aim of this study was to assess the hemodynamic effects of increasing hemoglobin concentration in human portal hypertension. ⋯ An increase in blood hemoglobin in acutely anemic cirrhotic patients attenuates their hyperdynamic circulation beyond viscosity-dependent changes, an effect which might be counteracted by the effects on portal venous pressure gradient.