Journal of critical care
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Journal of critical care · Oct 2015
Review Meta AnalysisE7ffect of critical care pharmacist's intervention on medication errors: A systematic review and meta-analysis of observational studies.
Pharmacists are integral members of the multidisciplinary team for critically ill patients. Multiple nonrandomized controlled studies have evaluated the outcomes of pharmacist interventions in the intensive care unit (ICU). This systematic review focuses on controlled clinical trials evaluating the effect of pharmacist intervention on medication errors (MEs) in ICU settings. ⋯ Four studies were included in the meta-analysis. Results suggest that pharmacist intervention has no significant contribution to reducing general MEs, although pharmacist intervention may significantly reduce preventable adverse drug events and prescribing errors. This meta-analysis highlights the need for high-quality studies to examine the effect of the critical care pharmacist.
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Journal of critical care · Oct 2015
Randomized Controlled Trial Multicenter StudyImproving rehabilitation after critical illness through outpatient physiotherapy classes and essential amino acid supplement: A randomized controlled trial.
Patients recovering from critical illness may be left with significant muscle mass loss. This study aimed to evaluate whether a 6-week program of enhanced physiotherapy and structured exercise (PEPSE) and an essential amino acid supplement drink (glutamine and essential amino acid mixture [GEAA]) improves physical and psychological recovery. ⋯ Enhanced rehabilitation combined with GEAA supplement may enhance physical recovery and reduce anxiety and depression.
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Journal of critical care · Oct 2015
Multicenter StudyFamilies' experiences of intensive care unit quality of care: Development and validation of a European questionnaire (euroQ2).
The purpose of the study is to adapt and provide preliminary validation for questionnaires evaluating families' experiences of quality of care for critically ill patients in the intensive care unit (ICU). ⋯ The questions were assessed as relevant and understandable, providing high face and content validity. Ceiling effects were comparable to similar instruments; missing data, low; and test-retest reliability, acceptable. These measures are promising for use in research, but further validation is needed before they can be recommended for routine clinical use.
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Journal of critical care · Oct 2015
Multicenter StudySustained low-efficiency dialysis with regional citrate anticoagulation in medical intensive care unit patients with liver failure: a prospective study.
Patients with liver failure requiring dialysis are at increased risk for citrate accumulation during sustained low-efficiency dialysis (SLED). The aim of this study was to evaluate the feasibilty of citrate SLED in critical ill patients with liver failure and investigate predictive parameters regarding citrate accumulation. ⋯ Despite substantial accumulation of citrate in serum, SLED is save and feasible in patients with liver failure using a citrate anticoagulation. Careful monitoring of electrolytes and acid base status is mandatory to ensure patient safety.
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Journal of critical care · Oct 2015
Multicenter StudyPostintubation hypotension in intensive care unit patients: A multicenter cohort study.
To determine the incidence of postintubation hypotension (PIH) and associated outcomes in critically ill patients requiring endotracheal intubation. ⋯ The development of PIH is common in ICU patients requiring emergency airway control and is associated with poor patient outcomes.