Journal of critical care
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Journal of critical care · Oct 2020
Multicenter Study Observational StudyInformed consent procedures in patients with an acute inability to provide informed consent: Policy and practice in the CENTER-TBI study.
Enrolling traumatic brain injury (TBI) patients with an inability to provide informed consent in research is challenging. Alternatives to patient consent are not sufficiently embedded in European and national legislation, which allows procedural variation and bias. We aimed to quantify variations in informed consent policy and practice. ⋯ Alternatives to patient consent are essential for TBI research. While there seems to be concordance amongst national legislations, there is regional variability in institutional practices with respect to the use of different informed consent procedures. Variation could be caused by several reasons, including inconsistencies in clear legislation or knowledge of such legislation amongst researchers.
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Journal of critical care · Oct 2020
Multicenter StudyClinical course after identification of new-onset atrial fibrillation in critically ill patients: The AFTER-ICU study.
Epidemiological information is lacking after identification of new-onset atrial fibrillation (AF) in critically ill patients. This study aimed to describe the clinical course after the identification of new-onset AF. ⋯ Although the proportion of patients with AF continued to decrease with various treatments, these patients had high risk of death. Further research to assess the management of new-onset AF in critically ill patients is warranted.