Critical care medicine
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To provide a conceptual and clinical review of Middle East respiratory syndrome. ⋯ This syndrome has raised global public health concerns about the dissemination of an emerging infectious disease and highlights the need for a coordinated global response to contain such a disease threat.
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Critical care medicine · Jun 2015
Effects of Proanthocyanidins on Adhesion, Growth, and Virulence of Highly Virulent Extraintestinal Pathogenic Escherichia coli Argue for Its Use to Treat Oropharyngeal Colonization and Prevent Ventilator-Associated Pneumonia.
In the context of increasing microbial resistance and limited new antimicrobials, we aimed to study the antimicrobial effects of cranberry proanthocyanidin extracts on Escherichia coli growth, adhesion to epithelial cells, and lung infection. ⋯ Cranberry proanthocyanidins exhibit potent effects on growth, adhesion, and virulence of oropharyngeal and lung isolates of E. coli, suggesting that cranberry proanthocyanidin could be of clinical interest to reduce oropharyngeal colonization and prevent lung infection.
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Critical care medicine · Jun 2015
Editorial CommentThe "big" dilemma: ICU volume-outcome relationships.
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Critical care medicine · Jun 2015
Editorial CommentFunctional outcomes after critical illness in the elderly.