Alimentary pharmacology & therapeutics

The most recent articles from: Aliment. Pharmacol. Ther. October 2014

Aliment. Pharmacol. Ther. · Oct 2014

Randomized Controlled Trial Multicenter Study

Randomised clinical trial: the long-term safety and tolerability of naloxegol in patients with pain and opioid-induced constipation.

Opioid-induced constipation (OIC) is a common adverse effect of opioid therapy. ⋯ In patients with noncancer pain and opioid-induced constipation, naloxegol 25 mg/day up to 52 weeks was generally safe and well tolerated.

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