Brain injury : [BI]
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Brain injury : [BI] · Jan 2014
ReviewWhere are we in the modelling of traumatic brain injury? Models complicated by secondary brain insults.
Traumatic brain injury (TBI) contributes to a substantial number of deaths and cases of disability. Despite well-established experimental models and years of carefully conducted research, a clinical therapeutic breakthrough in TBI has lagged. This may be due, in part, to the discrepancies between commonly used experimental models and clinical scenarios. ⋯ A more complete understanding of the interactions between the injured brain and secondary insults represents a potentially fruitful avenue that may increase the likelihood of developing effective therapies. Experimental models of TBI should not only attempt to model the focal or diffuse changes resulting from external forces, but also integrate, when appropriate, secondary insults reminiscent of human situations.
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Brain injury : [BI] · Jan 2014
Comparative StudyHospital admissions for traumatic brain injury of Austrian residents vs. of visitors to Austria.
The goal was to compare epidemiology of hospital admissions for traumatic brain injury (TBI) in Austrian residents vs. visitors to Austria. ⋯ Sports-related TBI of visitors causes a significant workload for Austrian hospitals. Better prevention is warranted.
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Brain injury : [BI] · Jan 2014
Randomized Controlled Trial Comparative StudySingle versus bilateral external ventricular drainage for intraventricular fibrinolysis using urokinase in severe ventricular haemorrhage.
Intraventricular fibrinolysis (IVF) through bilateral external ventricular drains (EVD) may provide better access of the thrombolytic agent to the intraventricular clot, potentially leading to faster clot clearance. ⋯ The results provide some evidence to support the use of bilateral EVDs for IVF in patients with severe IVH.
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Brain injury : [BI] · Jan 2014
Ten-year mortality after severe traumatic brain injury in western Sweden: a case control study.
Life expectancy may be substantially reduced for many years after severe traumatic brain injury (TBI). This study investigated the patterns of the short- and long-term all-cause mortality and the rates of primary causes of death in patients with severe TBI. ⋯ Further research will be required to determine how to improve treatment so as to lower late mortality among survivors of severe TBI.
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Brain injury : [BI] · Jan 2014
Effect of clinical characteristics on cognitive performance in service members and veterans with histories of blast-related mild traumatic brain injury.
To examine the relationship between clinical characteristics and cognitive performance in service members and veterans with histories of blast-related mild traumatic brain injury (mTBI). ⋯ This study demonstrated the importance of considering the effects of current clinical symptoms (e.g. post-traumatic stress) as possibly having greater influence on current cognitive functioning than the effects of a remote history of mTBI.