Journal of clinical anesthesia
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Randomized Controlled Trial Multicenter Study Clinical Trial
Timing of administration of dolasetron affects dose necessary to prevent postoperative nausea and vomiting.
To determine if the timing of administration affects the dose of dolasetron necessary to prevent postoperative nausea and vomiting (PONV). ⋯ When dosed near the end of anesthesia, a 12.5 mg IV dose of dolasetron was comparable to higher doses administered at or before induction of anesthesia.