Journal of clinical anesthesia
Randomized Controlled Trial Comparative Study
Nonsteroidal anti-inflammatory drugs (NSAIDs) play a role in pain relief, especially in postoperative pain caused by inflammation. They have demonstrated significant opioid dose-sparing effects, which help in reducing postoperative effects and opioid side effects. The objective of this meta-analysis was to explore the role of NSAIDs in reducing postoperative pain at different time intervals and provide reference for medication after lumbar spine surgery by a meta-analysis of randomized controlled trials (RCT). ⋯ NSAIDs are effective in postoperative analgesia after lumbar spine surgery. The study type, NSAID dose, different surgery types, and analgesic type might influence the efficacy of NSAIDs.
To review research highlights of manuscripts published in 2016 that pertain to all aspects of the clinical practice of anesthesiology. ⋯ This recent body of evidence will both help inform anesthesiologists of the developing trends in anesthesiology and will also pose new challenges for further studies.
Randomized Controlled Trial
To study the role of intravenous (i.v.) dexamethasone as an analgesic adjunct in labor analgesia. ⋯ I.v. dexamethasone significantly decreased hourly average drug consumption of levobupivacaine-fentanyl combination through the epidural route, demonstrating the epidural drug dose sparing effect during labor analgesia.
To determine the appropriate mean arterial pressure (MAP) control level for elderly patients with hypertension during the perioperative period. ⋯ For elderly hypertensive patients, controlling intraoperative MAP levels to 80 to 95mmHg can reduce postoperative AKI after major abdominal surgery.