BMJ : British medical journal
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Randomized Controlled Trial Multicenter Study Comparative Study
Ocular safety of sildenafil citrate when administered chronically for pulmonary arterial hypertension: results from phase III, randomised, double masked, placebo controlled trial and open label extension.
To assess the ocular effects and safety profile of chronic sildenafil oral dosing in patients with pulmonary arterial hypertension. ⋯ Sildenafil dosing up to 80 mg three times daily is safe and well tolerated from an ocular perspective in patients with pulmonary arterial hypertension. Daily chronic dosing in this patient population was not associated with visual change and had no detrimental effect on best corrected visual acuity, contrast sensitivity, colour vision, or visual field, or on slit lamp examinations, funduscopy, or intraocular pressure during the duration of this study.
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Randomized Controlled Trial Multicenter Study
Effectiveness of provider incentives for anaemia reduction in rural China: a cluster randomised trial.
To test the impact of provider performance pay for anaemia reduction in rural China. ⋯ Financial incentives for health improvement were modestly effective. Understanding interactions with other motives and pre-existing incentives is critical.