Journal of anesthesia
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Journal of anesthesia · Dec 1997
Normothermic cardiopulmonary bypass and cardioplegia reduce inotropic requirements and creatine kinase-MB after coronary artery bypass graft surgery.
To determine whether normothermic cardiopulmonary bypass (CPB) and cardioplegia preserve myocardial function, reduce inotropic requirements, and reduce markers of myocardial ischemia following coronary artery bypass graft surgery (CABG). ⋯ Normothermic CPB and cardioplegia reduce inotropic requirements and CK-MB following CABG.
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Journal of anesthesia · Dec 1997
Effect of inhaled nitroglycerine and sodium nitroprusside aerosol on hemodynamics and oxygenation in dogs with pulmonary hypertension.
To test the hypothesis that inhalation of aerosol of glyceryl trinitrate or sodium nitroprusside might produce selective pulmonary vasodilation, causing an improvement of oxygenation with minimal systemic hypotension as inhaled nitric oxide gas, we investigated the effect of inhaled nitroglycerine and sodium nitroprusside aerosol on hemodynamics and oxygenation in dogs with pulmonary hypertension. ⋯ These findings suggest that inhaled nitroglycerine and sodium nitroprusside aerosol is not effective in improving hemodynamic derangement or oxygenation in pulmonary hypertension. However, the effect of the substances in higher dose ranges remains to be defined.