European journal of internal medicine
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Eur. J. Intern. Med. · Jan 2025
Randomized Controlled Trial Multicenter StudyAssociation between trajectory of systolic blood pressure and outcomes in heart failure patients with preserved ejection fraction (HFpEF).
The optimal systolic blood pressure (SBP) in heart failure patients with preserved ejection fraction (HFpEF) remains controversial. We aim to assess the SBP trajectory and prognosis in HFpEF. ⋯ The decreasing or increasing SBP trajectory is associated with a high risk of cardiovascular events in HFpEF, suggesting a stable SBP trajectory group (≈130 mmHg) have lower incidence of cardiovascular events and mortality. Trials are necessary to determine the optimal SBP in HFpEF.